THE LI LABORATORY

Preprints: ​

1. Ito F., Zhang F., Li W. Time-Series RNA Sequencing Reveals Temperature-Specific and Temperature-Compensated Circadian Genes in Drosophila. https://doi.org/10.1101/2025.11.04.686609

2. Li Y., Feng D.**, Li W.** A Long-Term Drosophila Body Mass Measurement System. https://doi.org/10.1101/2025.05.29.656772

3. Gadau A., Mills S., Jiang Z., Li C., Svetec N., Xu Z., Li W., Nagel K.I., Zhao L. Molecular evolution of CO2-sensing ab1C neurons underlies divergent sensory responses in the Drosophila suzukii species group. https://www.biorxiv.org/content/10.1101/2025.11.21.689786v1

4. Doria E. I., Hammood F., Yan J., Li W. GIGEM (Group Isolation Gauge Effect Metrics), A Software Suite for Analyzing Social Isolation-induced Sleep Loss and Multi-Batch Experiments in Drosophila. https://www.biorxiv.org/content/10.64898/2025.12.18.695326v1

5. Li Y., Li W.**, Feng D.** A Vibration- and Vision-Based Method for Long-Term Drosophila Body Mass Monitoring. https://ssrn.com/abstract=5282331

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1. Wood N., Doria E.I., Rahman T.T., Li W., Pei Z., Qin H. (2025) Effects of Calcium Chloride Crosslinking Solution Concentration on the Long-Term Cell Viability of 16HBE14o- Human Bronchial Cells Embedded in Alginate-Based Hydrogels. Biomimetics (Basel). 2025 Jan 10;10(1):40. doi: 10.3390/biomimetics10010040. PMID: 39851756; PMCID: PMC11763177.

2. Zou L., Li W., Yang M., Lin B., Abedin J. (2023) The impact of social isolation on sleep disturbances – evidence from geospatial big data during COVID-19. In 31st International Cartographic Conference (ICC 2023), 6:293.

3. Wang Z., Nguyen A., Lincoln S., Li W.**, Young M.W.**. (2022) Chronic Sleep Loss Disrupts Rhythmic Gene Expression in Drosophila. Front Physiol. 2022 Nov 18;13:1048751. doi: 10.3389/fphys.2022.1048751.

4. Vora A., Nguyen A.D., Spicer C., Li W. (2022) The impact of social isolation on health and behavior in Drosophila melanogaster and beyond. Brain Science Advances. 2022;8(3):183-196.

5. Li W. and Keene A.C. (2021) Flies sense the world while sleeping. Nature, 598(7881):423-424.

6. Li W.**, Wang Z., Syed S., Lyu C., Lincoln S., O’Neil J., Nguyen A.D., Feng I., Young M.W.** (2021) Chronic social isolation signals starvation and reduces sleep in Drosophila. Nature, 597(7875):239-244 Highlighted in Levine J.D. (2021) Chronically lonely flies overeat and lose sleep. News and Views, Nature.

7. Ahmad M., Li W., Top, D. (2021) Integration of circadian clock information in the Drosophila circadian neuronal network. Journal of Biological Rhythms, 36(3):203-220.

8. Sun K.*, Garaulet D.L.*, Li W. *, Wen J., Hiesinger R., Young M.W., Lai E.C. (2016) Drosophila miR-124 regulates circadian activity phase by dampening BMP signaling. Journal of Neuroscience, 36 (12), 3414-3421.

9. Shuai Y., Hirokawa A., Ai Y., Zhang M., Li W., Zhong Y. (2015) Dissecting neural pathways for forgetting in Drosophila olfactory aversive memory. Proceedings of the National Academy of Sciences, 112 (48), E6663-E6672.

10. Campbell R.A., Honegger K.S., Qin H., Li W., Demir E., Turner G.C. (2013) Imaging a population code for odor identity in the Drosophila mushroom body. Journal of Neuroscience, 33(2.5):10568-81.

11. Li W.*, Prazak L.*, Chatterjee N., Grüninger S., Krug L., Theodorou D., Dubnau J. (2013) Activation of transposable elements during aging and neuronal decline in Drosophila. Nature Neuroscience, 16(5):529-31.

12. Li W., Cressy M., Qin H., Fulga T., Van Vactor D. Dubnau J. (2013) MicroRNA-276a functions in ellipsoid body and mushroom body neurons for naive and conditioned olfactory avoidance in Drosophila. Journal of Neuroscience, 33(13):5821-33.

13. Li W. and Dubnau J. (2012) A prion-mediated mechanism for memory proposed in Drosophila. Neuron, 76(2):260-2.

14. Li W.*, Jin Y.*, Prazak L.*, Hammel M., Dubnau J. (2012) Transposable elements in TDP-43-mediated neurodegenerative disorders. PLoS One, 7(9):e44099.

15. Qin H., Cressy M., Li W., Coravos J., Izzi S., Dubnau J. (2012) γ neurons are the gateway for DA input to Drosophila mushroom bodies for aversive olfactory memory formation. Current Biology, 10;22(7):608-14.

16. Blum A.L., Li W., Cressy M., Dubnau J.  (2009) Short- and long-term memory in Drosophila require cAMP signaling in distinct neuron types. Current Biology, 19(16):1341-50.

17. Chen G.*, Li W.*, Zhang Q.S.*, Regulski M., Sinha N., Barditch J., Tully T., Krainer A.R., Zhang M.Q., Dubnau J. (2008) Identification of synaptic targets of Drosophila pumilio. PLoS Computational Biology, 4(2):e1000026.

       

       **co-corresponding authors    *contribute equally